Author

Nadine Brückner

Medizinische Hochschule HannoverORCID 0009-0008-4658-3279Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Abel Viejo‐BorbollaiD· 1 shared Adam T. GrundhoffiD· 1 shared Ariane Metzger· 1 shared Benedikt B. KauferiD· 1 shared Birgit RitteriD· 1 shared Carolin VogtiD· 1 shared Daniel P. DepledgeiD· 1 shared Gundram JungiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

Abel Viejo‐BorbollaORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 20, 2026

Bivalent bispecific CD28 antibodies reinforce T-cell responsiveness and revert anergy/quiescence in patients treated with bispecific CD3 antibodies

Latifa Zekri, Natalie Köhler, Ariane Metzger…·Helmut Rainer Salih

This paper develops bispecific costimulators (BiCos) that restore T-cell function in patients treated with bispecific CD3 antibodies, reversing anergy and quiescence through enhanced signaling.

DOI 10.64898/2026.03.25.714198

humanscRNA-seq

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MicrobiologyPLoS PathogensPeer-reviewedFeb 10, 2025

Repression of varicella zoster virus gene expression during quiescent infection in the absence of detectable histone deposition

Jiayi Wang, Nadine Brückner, Simon Weissmann…·Abel Viejo‐Borbolla

This study investigates VZV gene repression in neuronal cells, finding that histone deposition is absent at quiescent viral genomes.

8 citationstop 4%

humanbulk RNA-seq

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