Opposing roles of ACE2 and TMPRSS2 in IBV Beaudette infection
Yuan Cao, Yannis Long, Sabrina Schleibinger…·Hicham Sid
This study identifies ACE2 as a proviral host factor and TMPRSS2 as a restrictive factor for IBV BD infection in chicken cells.
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Freie Universität BerlinORCID 0000-0003-1328-2695Unclaimed ORCID profile · follow to get notified of new preprints
7 papers
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Yuan Cao, Yannis Long, Sabrina Schleibinger…·Hicham Sid
This study identifies ACE2 as a proviral host factor and TMPRSS2 as a restrictive factor for IBV BD infection in chicken cells.
Dennis Freisem, Daniel Rombach, Sarah J. Brockmann…·Karin M. Danzer
This study shows HSV infection increases ALS risk and promotes TDP-43 pathology through ICP0-mediated disruption of PML bodies.
Jiayi Wang, Nadine Brückner, Simon Weissmann…·Abel Viejo‐Borbolla
This study investigates VZV gene repression in neuronal cells, finding that histone deposition is absent at quiescent viral genomes.
Timothy K. Soh, Sofia Ognibene, Saskia Sanders…·Jens B. Bosse
The paper provides proteome-wide structure predictions for all human herpesviruses and identifies new protein families and potential functions through structural analysis.
Mohammad A. Sabsabi, Ahmed Kheimar, Yu You…·Benedikt B. Kaufer
This study shows that γδ T cells restrict Marek's disease virus replication and tumor formation in chickens by reducing viral load in key lymphoid organs.
Denise Bartsch, Hicham Sid, Beate Rieblinger…·Benjamin Schusser
This paper generates Cas9-expressing transgenic chickens and pigs for in vivo genome editing, demonstrating their health, fertility, and functionality across multiple tissues and genes.
Shella Gilbert-Girard, Annie Gravel, Vanessa Collin…·Louis Flamand
This study shows HHV-6A/B infections increase telomeric signals and recruit TRF2 to viral telomeres, suggesting a role for shelterin proteins in viral integration.