Author

Chhandosee Ganguly

University of OklahomaORCID 0009-0008-5135-5318Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Leonard M. ThomasiD· 1 shared Lindsie Martin· 1 shared Rakhi RajaniD· 1 shared Swarmistha Devi AribamiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

Leonard M. ThomasORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

BiochemistrybioRxivPreprintJan 9, 2025

Helical transition of the bridge helix of Cas12a is an allosteric regulator of R-loop formation and RuvC activation

Chhandosee Ganguly, Lindsie Martin, Swarmistha Devi Aribam…·Rakhi Rajan

This study investigates how the bridge helix (BH) of Cas12a regulates R-loop formation and RuvC activation through conformational changes, revealing structural mechanisms for improving Cas12a specificity.

DOI 10.1101/2025.01.09.632262

structural biologyexperimental assay

𝕏 PostBluesky