Wenyuan Wei

The paper identifies subtype-specific conserved residues in G protein subtypes that modulate Gβγ coupling, showing conservation does not guarantee functional equivalence.

The paper identifies frustrated residues in GPCR:G protein interfaces and engineered degrader complexes, showing higher frustration in engineered interfaces.

BaNDyT uses Bayesian network modeling to analyze molecular dynamics trajectories, providing data-driven insights into protein function and interactions.

This study uses protein frustration analysis to identify key residues distinguishing strong from weak BRD4-Cereblon degraders.