Author

Freya Kirwan

Emma KinderziekenhuisORCID 0009-0008-5223-5887Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Neuroscience· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Aleksandra BaduraiD· 1 shared Amélie FrealiD· 1 shared Catarina OsórioiD· 1 shared Elena AmbrosiniiD· 1 shared Eleonora RegoloiD· 1 shared Emma M. J. PasschieriD· 1 shared Federico Olivero· 1 shared Francesca Romana FiocchiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperNeuroscience

Aleksandra BaduraORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

NeuroscienceNature CommunicationsPeer-reviewedMar 9, 2026

Purkinje cell intrinsic activity shapes cerebellar development and function

Catarina Osório, Joshua J. White, Paula Torrents-Solé…·Martijn Schonewille

This study shows that Purkinje cell intrinsic activity before synaptic maturation is critical for dendrite growth, connectivity, and cerebellar function, with early disruptions causing severe morphological and functional defects.

3 citations

mousebulk RNA-seq

𝕏 PostBluesky

NeuroscienceGliaPeer-reviewedDec 2, 2025

Altered mechanical properties of astrocytes lacking MLC1; implications for the leukodystrophy MLC

Quinty Bisseling, Emma M. J. Passchier, Freya Kirwan…·Rogier Min

This study shows that Mlc1-null astrocytes are softer and have altered cytoskeleton-membrane-ECM interactions, suggesting a role for mechanobiology in MLC pathogenesis.

2 citations

mousestatistical model

𝕏 PostBluesky