BiochemistrybioRxivPreprint
Changing expression system alters oligomerization and proinflammatory activity of recombinant human S100A9
Lauren O. Chisholm, Chae Kyung Jeon, James S. Prell, Michael J. Harms
This study shows that recombinant S100A9 expressed in insect cells lacks TLR4 activation compared to E. coli-expressed S100A9, due to altered oligomerization.
DOI 10.1101/2024.08.14.608001