Author

Max Tiessen

Leibniz Institute on Aging - Fritz Lipmann Institute (FLI)ORCID 0009-0008-5534-0578Unclaimed ORCID profile · follow to get notified of new preprints

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Max Tiessen1 paper · Osnabrück University

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Systems Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:proteomics· 1 Approach:statistical model· 1 Organism:zebrafish· 1

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Alessandro CellerinoiD· 1 shared Alessandro Ori‬‬iD· 1 shared Amit Kumar SahuiD· 1 shared Antonio MarinoiD· 1 shared Domenico Di FraiaiD· 1 shared Erika Kelmer SacramentoiD· 1 shared Eva Terzibasi-Tozzini· 1 shared Giacomo SianoiD· 1 shared

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2023-2023 · peak 1/yr

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Alessandro CellerinoORCID

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1 paper

Recent·Most cited

Systems BiologybioRxivPreprintJul 20, 2023

Impaired biogenesis of basic proteins impacts multiple hallmarks of the aging brain

Domenico Di Fraia, Antonio Marino, Jae Ho Lee…·Alessandro Ori‬‬

The paper shows that aging in killifish brains reduces basic amino acid-rich proteins through translation pausing, not transcription or proteasome issues, revealing a vulnerability in nucleic-acid protein biogenesis.

14 citations

zebrafishbulk RNA-seq

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