Author

Sebastian Bieker

Osnabrück UniversityORCID 0009-0008-8091-3550Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

Chelsea M. BrowniD· 1 shared D. G. HassaniD· 1 shared Joost C. M. HolthuisiD· 1 shared Manuel N. MeloiD· 1 shared Michael TimmeiD· 1 shared Nils Woge· 1 shared ‪Siewert J. MarrinkiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Chelsea M. BrownORCID

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1 paper

Recent·Most cited

BiochemistryCommunications BiologyPeer-reviewedFeb 10, 2025

Hexokinase-I directly binds to a charged membrane-buried glutamate of mitochondrial VDAC1 and VDAC2

Sebastian Bieker, Michael Timme, Nils Woge…·Joost C. M. Holthuis

This study identifies a charged glutamate on VDAC1 and VDAC2 that interacts with HKI's N-terminal helix, revealing structural and mechanistic insights into their complex formation.

33 citationstop 1%

experimental assaystatistical model

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