Author

Simone Ritchey

The University of Texas at AustinORCID 0009-0008-8329-4687Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Anthony A. KossiakoffiD· 1 shared Axel F. BrilotiD· 1 shared Caitlyn L McCaffertyiD· 1 shared David Ward TayloriD· 1 shared Edward M. MarcotteiD· 1 shared Evan A. SchwartziD· 1 shared Gabriel HoogerbruggeiD· 1 shared Jane E. Lodwick· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Anthony A. KossiakoffORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintSep 22, 2025

The CAGE complex: a hollow, megadalton, protein assembly in prokaryotic and eukaryotic microbes

Caitlyn L McCafferty, Gabriel Hoogerbrugge, Ophelia Papoulas…·Edward M. Marcotte

The paper identifies and characterizes a new conserved protein complex, CAGE, found in both prokaryotes and eukaryotes, revealing its structural features and evolutionary distribution.

1 citation

humanmouse

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BiochemistryNature CommunicationsPeer-reviewedJul 21, 2025

Structural Insights into the Roles of PARP4 and NAD+ in the Human Vault Cage

Jane E. Lodwick, Rong Shen, Satchal K. Erramilli…·Minglei Zhao

This study determines the structure of the human vault cage with PARP4 and NAD+, revealing binding interfaces and NAD+ pockets, and shows proteomics differences in PARP4-depleted vaults.

8 citations

humanstructural biology

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