Author

Benedetta Manzato

Leiden University Medical CenterORCID 0009-0008-8369-2327Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Assay:metabolomics· 2 Assay:spatial transcriptomics· 2 Research Focus:batch correction / integration· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Ahmed Essam MahfouziD· 2 shared Gangqi WangiD· 2 shared Rosalie G. J. RietjensiD· 2 shared Sébastien J. DumasiD· 2 shared Ton J. RabelinkiD· 2 shared Bernard M. van den BergiD· 1 shared Christos Botos· 1 shared Claudio Novella-RauselliD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBioinformatics

Ahmed Essam MahfouzORCID

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2 papers

Recent·Most cited

BioinformaticsCell Reports MethodsPeer-reviewedSep 1, 2026

Image-guided alignment of consecutive multi-modal tissue slides

Benedetta Manzato, Claudio Novella-Rausell, Gangqi Wang…·Ahmed Essam Mahfouz

COAST aligns consecutive tissue sections using only spatial images, enabling unified multi-modal molecular data analysis without molecular markers or annotations.

DOI 10.1016/j.crmeth.2026.101575

mousespatial transcriptomics

𝕏 PostBluesky

BiochemistryJournal of the American Society of NephrologyPeer-reviewedAug 3, 2026

Spatial metabolomics reveals persistent localized niche-specific metabolic failure in kidneys following ischemia-reperfusion injury

Rosalie G. J. Rietjens, Benedetta Manzato, Yuheng Liao…·Ton J. Rabelink

The paper uses spatial metabolomics and transcriptomics to identify persistent metabolic failure in kidney niches after ischemia-reperfusion injury, highlighting mitochondrial dysfunction in otherwise healthy areas.

DOI 10.1681/asn.0000001216

humanspatial transcriptomics

𝕏 PostBluesky