Author

Rosalie G. J. Rietjens

Leiden University Medical CenterORCID 0000-0002-8618-4482Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:metabolomics· 2 Organism:mouse· 2 Assay:spatial transcriptomics· 2 Research Focus:batch correction / integration· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Ahmed Essam MahfouziD· 2 shared Benedetta ManzatoiD· 2 shared Gangqi WangiD· 2 shared Sébastien J. DumasiD· 2 shared Ton J. RabelinkiD· 2 shared Aaron N. Chang· 1 shared Andrew S. KhaliliD· 1 shared Angela M. CacaceiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBioinformatics

Ahmed Essam MahfouzORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BioinformaticsCell Reports MethodsPeer-reviewedSep 1, 2026

Image-guided alignment of consecutive multi-modal tissue slides

Benedetta Manzato, Claudio Novella-Rausell, Gangqi Wang…·Ahmed Essam Mahfouz

COAST aligns consecutive tissue sections using only spatial images, enabling unified multi-modal molecular data analysis without molecular markers or annotations.

DOI 10.1016/j.crmeth.2026.101575

mousespatial transcriptomics

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BiochemistryJournal of the American Society of NephrologyPeer-reviewedAug 3, 2026

Spatial metabolomics reveals persistent localized niche-specific metabolic failure in kidneys following ischemia-reperfusion injury

Rosalie G. J. Rietjens, Benedetta Manzato, Yuheng Liao…·Ton J. Rabelink

The paper uses spatial metabolomics and transcriptomics to identify persistent metabolic failure in kidney niches after ischemia-reperfusion injury, highlighting mitochondrial dysfunction in otherwise healthy areas.

DOI 10.1681/asn.0000001216

humanspatial transcriptomics

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NeuroscienceBiological PsychiatryPeer-reviewedJan 1, 2023

Fragile X syndrome patient-derived neurons developing in the mouse brain show FMR1 -dependent phenotypes

Marine Krzisch, Hao Wu, Bingbing Yuan…·Rudolf Jaenisch

This study transplants FXS patient-derived neurons into mice to study their development and finds FMR1-dependent changes in synaptic activity and morphology.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky