Author

L CHEN

University of TorontoORCID 0009-0008-8748-3602Unclaimed ORCID profile · follow to get notified of new preprints

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L Chen2 papers · Emory University

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Pharmacology & Toxicology· 1

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Research Focus:benchmarking· 1 Organism:C. elegans· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrew R. BurnsiD· 1 shared Arthur FlagetiD· 1 shared Brenda AndrewsiD· 1 shared Brittany CookeiD· 1 shared Charles M. BooneiD· 1 shared Ermira Shuteriqi· 1 shared Guihong TaniD· 1 shared Irini TopalidouiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

Andrew R. BurnsORCID

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1 paper

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintJul 16, 2026

The Nematicide Tioxazafen Disrupts Proteasome Function via Cytochrome P450 Bioactivation

L CHEN, Kaiden Thompson, Muntasir Kamal…·Peter John Roy

This study shows tioxazafen is bioactivated by cytochrome P450s into a proteasome disruptor, leading to toxicity in nematodes and potential human skin reactions.

DOI 10.64898/2026.07.10.737828

C. eleganshuman