Overexpression of Eaf1, a subunit of the NuA4 lysine acetyltransferase complex, rescues growth defects in the budding yeast H3K36M oncohistone model via histone H4 tail acetylation
Celina Y. Jones, L Chen, Milo B. Fasken, Anita H. Corbett, Jennifer M. Spangle
This paper shows that overexpressing Eaf1, a NuA4 subunit, rescues growth defects in yeast with H3K36M mutations by acetylating histone H4 tails.
bioRxiv · Jun 26, 2026 · PreprintGenetics