Dean Light

This study shows ADARs prevent RNAi from targeting self-produced dsRNA by reducing siRNA production and interfering with RNAi processing in C. elegans.

RESIC identifies and classifies A-to-I RNA editing sites across organisms and datasets, showing increased hyper-editing and ADAR1 activity in SARS-CoV-2 infected cells.

BiSEK improves differential expression analysis by identifying affected pathways without relying on individual gene significance, showing results relevant to FUBP1 depletion and SARS-CoV-2 infection.

The paper introduces QsRNA-seq, a method for high-throughput profiling of small RNAs, showing it accurately quantifies miRNAs and identifies developmentally specific miRNAs in C. elegans.