Cell BiologyNature CommunicationsPeer-reviewed
Suppression of TGF-β/SMAD signaling by an inner nuclear membrane phosphatase complex
Zhe Ji, Wingyan Skyla Siu, María Emilia Dueñas…·Pedro Carvalho
The paper identifies CTDNEP1-NEP1R1 as the R-SMAD phosphatase and shows how its complex with MAN1 inactivates TGF-β signaling by dephosphorylating R-SMADs in the nucleus.
7 citations