Author

Huynh T.H. Nguyen

The University of MelbourneORCID 0009-0008-9826-8457Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Alexa R Prawdiuk· 2 shared Jessica L. FletcheriD· 2 shared Junhua XiaoiD· 2 shared Rhiannon J. Wood· 2 shared Simon S. MurrayiD· 2 shared Christine M.K. Jun· 1 shared David G. GonsalveziD· 1 shared Eleanor M. L. NormaniD· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Alexa R Prawdiuk

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2 papers

Recent·Most cited

NeuroscienceFrontiers in Molecular NeurosciencePeer-reviewedAug 27, 2019

TrkB Agonist LM22A-4 Increases Oligodendroglial Populations During Myelin Repair in the Brain

Huynh T.H. Nguyen, Rhiannon J. Wood, Alexa R Prawdiuk…·Jessica L. Fletcher

This study compares two TrkB agonists, TDP6 and LM22A-4, in a mouse model of demyelination, finding that LM22A-4 promotes remyelination via indirect Trk receptor transactivation.

38 citations

mousebulk RNA-seq

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NeuroscienceJournal of NeurosciencePeer-reviewedJul 5, 2018

Targeting TrkB with a brain-derived neurotrophic factor mimetic promotes myelin repair in the brain

Jessica L. Fletcher, Rhiannon J. Wood, Jacqueline K. Nguyen…·Simon S. Murray

This study shows that a BDNF mimetic targeting TrkB promotes myelin repair in a mouse model of demyelination by enhancing oligodendrocyte differentiation and remyelination.

81 citationstop 2%

mouseexperimental assay

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