Author

Kelvin Dempster

The Francis Crick InstituteORCID 0009-0009-0750-0175Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Assay:metagenomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Margaux SilvestreiD· 2 shared Sila K. UltaniriD· 2 shared Alex N. BullockiD· 1 shared Alison Donnelly AxtmaniD· 1 shared Almaz Huseynova· 1 shared André T. LopesiD· 1 shared Anna M. Castano· 1 shared Carla A. Ferrer· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersNeuroscience

Margaux SilvestreORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintMay 29, 2026

CDKL5 phosphorylates neuronal ELAVL proteins to promote mRNA binding, protein synthesis and visual cortex development

Simeon R. Mihaylov, André T. Lopes, Margaux Silvestre…·Sila K. Ultanir

This study identifies CDKL5 as a kinase that phosphorylates nELAVL proteins, enhancing mRNA binding and protein synthesis, and shows its role in visual cortex development.

DOI 10.64898/2026.04.07.716766

mouseproteomics

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NeuroscienceeLifePeer-reviewedJul 25, 2023

Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology

Anna M. Castano, Margaux Silvestre, Carrow I. Wells…·Alison Donnelly Axtman

The paper develops specific CDKL5 inhibitors that do not affect GSK3β activity and shows their effects on synaptic function and LTP in rat hippocampal slices.

15 citations

ratelectronic health records

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