BioengineeringbioRxiv
Compositional editing of extracellular matrices by CRISPR/Cas9 engineering of human mesenchymal stem cell lines
Sujeethkumar Prithiviraj, Alejandro Garcia Garcia, Karin Linderfalk…·Paul Emile Bourgine
This study uses CRISPR/Cas9 to edit human mesenchymal stem cells to produce engineered extracellular matrices with modified VEGF and RUNX2 expression, showing altered osteogenic properties.