Alan Cieslukowski

This study shows TREM2's role in glioblastoma depends on genetic context and timing, with different effects in Nf1-silenced/Ras-driven and PDGFB-driven models.

This study shows that increased Spy1 expression in neural stem cells enhances stemness, reduces differentiation, and promotes oncogenic transformation in mice.

The paper describes methods to study 3D cell cycle dynamics of glioma stem cells using fluorescent reporter systems and bioinformatics analysis.

This paper describes methods for generating zebrafish PDX systems to study GSC-mediated tumorigenesis and interactions with the tumor microenvironment.