Author

Nathan H. Lee

University of California San DiegoORCID 0009-0009-1790-5387Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Calvin P. LiniD· 1 shared Elizabeth A. KomivesiD· 1 shared Francis X. Alipranti· 1 shared Harry LiiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperBiochemistry

Calvin P. LinORCID

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1 paper

Recent·Most cited

BiochemistryMolecular & Cellular ProteomicsPeer-reviewedNov 20, 2025

The Mechanism of Histone Ubiquitylation by the ASB9-CUL5 Ubiquitin Ligase

Calvin P. Lin, Nathan H. Lee, Francis X. Alipranti…·Elizabeth A. Komives

This paper shows that the ASB9-CRL ubiquitin ligase polyubiquitylates histones H3 and H4, but not H2A and H2B, and that this process requires ARIH2 and occurs only on free histones.

DOI 10.1016/j.mcpro.2025.101471

proteomicsexperimental assay

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