Cell BiologyNature CommunicationsPeer-reviewed
Aneuploidy-induced proteostasis disruption impairsmitochondrial functions and mediates aggregation ofmitochondrial precursor proteins through SQSTM1/p62
Prince Saforo Amponsah, Jan-Eric Boekenkamp, Olha Kurpa…·Zuzana Štorchová
This study shows that aneuploidy disrupts proteostasis, leading to mitochondrial dysfunction and accumulation of mitochondrial precursor proteins in cytosolic p62 bodies.
15 citations