Prince Saforo Amponsah

This study shows that polyploidy leads to reduced mitochondrial scaling and impaired metabolic function, with conserved effects across yeast and human cells.

This study shows that aneuploidy disrupts proteostasis, leading to mitochondrial dysfunction and accumulation of mitochondrial precursor proteins in cytosolic p62 bodies.

This study identifies Tsa1 as the primary peroxide scavenger in yeast and shows it can generate GSSG under H2O2 conditions.