Author

Paula Santos Otte

Center for Molecular BioengineeringORCID 0009-0009-4556-0574Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Caroline BraeuningiD· 1 shared Cordula ReutheriD· 1 shared Elisabeth FritschiD· 1 shared Ilaria PiazzaiD· 1 shared Jana RossiusiD· 1 shared Kamelija Horvatović· 1 shared Laura BreimanniD· 1 shared Melissa BiroliD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Caroline BraeuningORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJun 23, 2026

Spreading α-synuclein rewires organelle communication and impairs neuron-astrocyte mitochondrial quality control

Elisabeth Fritsch, Kamelija Horvatović, Paula Santos Otte…·Melissa Birol

This study shows that spreading α-synuclein alters organelle communication and disrupts neuron-astrocyte mitochondrial quality control.

DOI 10.64898/2026.06.19.733342

humanproteomics

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BiophysicsJournal of Cell SciencePeer-reviewedFeb 23, 2026

Microtubule lattice defects facilitate spastin-mediated severing

Cordula Reuther, Paula Santos‐Otte, Rahul Grover…·Stefan Diez

This study shows that microtubule lattice defects accelerate spastin-mediated severing by reducing the number of tubulin subunits needed for cleavage, without preferential spastin binding to defects.

5 citationstop 1%

experimental assay

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