BiochemistryProceedings of the National Academy of SciencesPeer-reviewed
Soluble guanylyl cyclase, the NO-receptor, regulates endothelium-dependent vascular relaxation via its transnitrosation activity.
Waqas Younis, Pía C. Burboa, Tanaz Sadeghian…·Annie V. Beuve
This study shows that the C610S mutation in GC1 disrupts endothelium-dependent vascular relaxation by impairing S-nitrosation, despite normal NO-cGMP signaling.
6 citations