Mauricio A. Lillo

This study shows that reducing S-nitrosylation of Cx43 in DMD mice prevents arrhythmias and myocardial injury under cardiac stress.

This study shows that the C610S mutation in GC1 disrupts endothelium-dependent vascular relaxation by impairing S-nitrosation, despite normal NO-cGMP signaling.

This study shows TRPV4 activation modulates endothelial Cx43 hemichannels via S-nitrosylation, influencing Ca2+ levels and vasomotor tone in resistance arteries.

This study shows that Cx43 hemichannels in astrocytes contribute to ALS progression and that blocking them can protect neurons and improve survival in ALS models.