Annie V. Beuve

This study shows that a low-androgen environment maintains redox-active sGC states, enhancing riociguat efficacy in castration-resistant prostate cancer by increasing cGMP levels.

This study shows that the C610S mutation in GC1 disrupts endothelium-dependent vascular relaxation by impairing S-nitrosation, despite normal NO-cGMP signaling.

This study shows TRPV4 activation modulates endothelial Cx43 hemichannels via S-nitrosylation, influencing Ca2+ levels and vasomotor tone in resistance arteries.