Author

Yu-Syuan Wu

Boston Children's HospitalORCID 0009-0009-6672-0135Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Approach:statistical model· 1

Frequent Co-Authors

Amy E. O’ConnelliD· 3 shared Luiz Fernando Silva OliveiraiD· 3 shared Comfort AdegboyeiD· 2 shared David T. BreaultiD· 2 shared Jaedeok Kwon· 2 shared Venkata Siva Dasuri· 2 shared Amanda W. Harrington· 1 shared Chidera Emeonye· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersDevelopmental Biology

Amy E. O’ConnellORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 21, 2025

Loss of WNT2B Increases Progression from Dysplasia to Colorectal Cancer

Luiz Fernando Silva Oliveira, Yu-Syuan Wu, Sathuwarman Raveenthiraraj…·Amy E. O’Connell

This study shows that loss of WNT2B promotes colorectal cancer progression in mouse models and is associated with poor patient survival in human samples.

DOI 10.1101/2025.08.21.671161

mousebulk RNA-seq

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Developmental BiologybioRxivPreprintJan 7, 2025

Necrotizing enterocolitis causes increased ileal goblet cell loss in Wnt2b KO mice

Comfort Adegboye, Chidera Emeonye, Yu-Syuan Wu…·Amy E. O’Connell

This study investigates the role of WNT2B in small intestinal injury during necrotizing enterocolitis in Wnt2b KO mice, finding no significant impact on ileal injury or goblet cell markers.

1 citation

mouseexperimental assay

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Developmental BiologybioRxivPreprintSep 25, 2024

Cataloguing the mouse small intestinal transcriptome in duodenum and ileum during the first postnatal month

Luiz Fernando Silva Oliveira, Radhika S. Khetani, Nicholas Makogonov…·Amy E. O’Connell

The paper uses bulk RNA-Seq to analyze gene expression changes in mouse duodenum and ileum during the first postnatal month, identifying key molecular shifts and comparing them to human data.

1 citation

mousebulk RNA-seq

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