Author

Jaedeok Kwon

Boston Children's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Amy E. O’ConnelliD· 2 shared Comfort AdegboyeiD· 2 shared Luiz Fernando Silva OliveiraiD· 2 shared Yu-Syuan WuiD· 2 shared Alison McColliD· 1 shared BRIAN J. MORRISiD· 1 shared Chidera Emeonye· 1 shared David T. BreaultiD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersCancer Biology

Amy E. O’ConnellORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Loss of WNT2B Increases Progression from Dysplasia to Colorectal Cancer

Luiz Fernando Silva Oliveira, Yu-Syuan Wu, Sathuwarman Raveenthiraraj, Jaedeok Kwon, Venkata Siva Dasuri, Comfort Adegboye, Juan Putra, Jorge O. Múnera, Diana L. Carlone, David T. Breault, Amy E. O’Connell

This study shows that loss of WNT2B promotes colorectal cancer progression in mouse models and is associated with poor patient survival in human samples.

bioRxiv · Aug 21, 2025 · PreprintCancer Biology

Necrotizing enterocolitis causes increased ileal goblet cell loss in Wnt2b KO mice

Comfort Adegboye, Chidera Emeonye, Yu-Syuan Wu, Jaedeok Kwon, Luiz Fernando Silva Oliveira, Sathuwarman Raveeniraraj, Amy E. O’Connell

This study investigates the role of WNT2B in small intestinal injury during necrotizing enterocolitis in Wnt2b KO mice, finding no significant impact on ileal injury or goblet cell markers.

bioRxiv · Jan 7, 2025 · PreprintDevelopmental Biology

Distinct trans-placental effects of maternal immune activation by TLR3 and TLR7 agonists: implications for schizophrenia risk

Jaedeok Kwon, Maria Suessmilch, Alison McColl, Jonathan Cavanagh, BRIAN J. MORRIS

This study compares the effects of TLR3 and TLR7 agonists on maternal blood, placenta, and fetal brain in mice, revealing distinct immune responses and implications for schizophrenia risk.

Scientific Reports · Dec 13, 2021Peer-reviewedNeuroscience