Author

Jia Li Ye

Medizinische Hochschule HannoverORCID 0009-0009-7658-4173Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:proteomics· 2

Frequent Co-Authors

Christian BäriD· 3 shared Thomas ThumiD· 3 shared Lea OehlseniD· 2 shared Malte JuchemiD· 2 shared Ajinkya Kulkarni· 1 shared Amara Khan· 1 shared Amir Moussavi· 1 shared Boguslawa SadowskiiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersMolecular Biology

Christian BärORCID

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3 papers

Recent·Most cited

PhysiologybioRxivPreprintMay 12, 2026

Natural aging drives a subclinical cardiovascular phenotype in a non-human primate

Lina Klösener, Mostafa Samak, Dominik Lerm…·Rabea Hinkel

This study examines natural cardiovascular aging in non-human primates, finding histological and molecular changes associated with aging, including fibrosis, inflammation, and atherosclerosis.

DOI 10.64898/2026.05.08.723137

non-human primatebulk RNA-seq

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Molecular BiologybioRxivPreprintDec 5, 2025

Nucleoside-Modified mRNA Encoding Alpha-Galactosidase A Reverses Fabry Disease Phenotypes in Human IPSC-Derived Cardiomyocytes

Malte Juchem, Sedef Ersoy, Lea Oehlsen…·Thomas Thum

This study shows that modGLA mRNA therapy reverses Fabry disease phenotypes in human iPSC-derived cardiomyocytes by restoring enzyme activity and normalizing molecular alterations.

DOI 10.64898/2025.12.03.692072

humanbulk RNA-seq

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Molecular BiologyAging CellPeer-reviewedSep 20, 2025

Telomerase modRNA offers a novel RNA-based approach to treat human pulmonary fibrosis

Jia Li Ye, Klaudia Maria Grieger, Dongchao Lu…·Christian Bär

This study demonstrates that modRNA hTERT treatment reduces fibrosis markers and senescence in human lung cells and tissue slices.

2 citations

humanbulk RNA-seq

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