Author

Zaid Hatem

Vanderbilt University Medical CenterORCID 0009-0009-7716-2845Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Allison E. SewelliD· 2 shared Darren R. HeintzmaniD· 2 shared Emily Nicole ArneriD· 2 shared Erin Q. JenningsiD· 2 shared Jeffrey C. RathmelliD· 2 shared KayLee K. SteineriD· 2 shared A. R. ZhelonkiniD· 1 shared Alexander M. BlattiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersImmunology

Allison E. SewellORCID

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2 papers

Recent·Most cited

ImmunologyThe Journal of ImmunologyPeer-reviewedApr 9, 2025

Mitochondrial Fatty Acid Synthesis and Mecr Regulate CD4+ T Cell Function and Oxidative Metabolism

KayLee K. Steiner, Arissa Young, Andrew R. Patterson…·Jeffrey C. Rathmell

This study shows that Mecr, a mitochondrial fatty acid synthesis gene, is critical for CD4+ T cell metabolism, function, and survival, with implications for inflammatory diseases and mitochondrial disorders.

19 citationstop 2%

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJan 8, 2025

Impaired oxidative phosphorylation drives primary tumor escape and metastasis

Emily Nicole Arner, Erin Q. Jennings, Daniel R. Crooks…·Jeffrey C. Rathmell

This study shows that impaired oxidative phosphorylation, driven by NDUFA4L2, promotes EMT and metastasis in renal cell carcinoma by altering chromatin accessibility.

4 citations

humanbulk RNA-seq

𝕏 PostBluesky