BiophysicsAdvanced SciencePeer-reviewed
A Phosphorylation-Induced Micellization switch in the low complexity domain of TDP-43
Rodrigo F. Dillenburg, Lopatina Anastasia, Hao Ruan…·Edward A. Lemke
This study shows phosphorylation of TDP-43's low-complexity domain shifts its self-assembly from macrophase separation to micellization, potentially protecting against pathological aggregation.
DOI 10.1002/advs.76625