Carla Schmidt

This study investigates how TDP-43 phase separation affects its protein interactome and regulation of alternative splicing, showing PS-dependent interactions with RNA regulators.

This study shows phosphorylation of TDP-43's low-complexity domain shifts its self-assembly from macrophase separation to micellization, potentially protecting against pathological aggregation.

This study investigates the molecular mechanisms of TCV P38, a viral protein with dual functions as an RNAi suppressor and capsid-forming protein, revealing its structural flexibility and domain interactions.

The paper shows IM30 binds membranes via a conserved helical hairpin, initiating assembly into higher-order structures that mediate membrane remodeling, revealing a conserved mechanism across ESCRT-III superfamily members.