Author

Luc Brunel

École Nationale Supérieure de Chimie de MontpellierORCID 0009-0009-8446-1923Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Alain ChavanieuiD· 1 shared Anthony R. MartiniD· 1 shared Baptiste LegrandiD· 1 shared Émilie Rigal· 1 shared Guillaume LacondeiD· 1 shared Jean‐Marc PascussiiD· 1 shared Julie PannequiniD· 1 shared Lucile Bansard· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alain ChavanieuORCID

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1 paper

Recent·Most cited

Cancer BiologyOncogenesisPeer-reviewedAug 30, 2025

Targeting Pregnane X Receptor with a Potent Agonist-Based PROTAC to Delay Colon Cancer Relapse

Lucile Bansard, Guillaume Laconde, Vanessa Delfosse…·Jean‐Marc Pascussi

This study designs and tests a PXR agonist-based PROTAC (JMV7048) that degrades PXR in cancer cells, reducing chemoresistance and delaying colon cancer relapse.

8 citations

humanexperimental assay

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