Author

Alain Chavanieu

École Nationale Supérieure de Chimie de MontpellierORCID 0000-0002-0512-5115Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

Jean‐Marc PascussiiD· 2 shared Julie PannequiniD· 2 shared Anthony R. MartiniD· 1 shared Antoine Aze· 1 shared Aurore SiegfriediD· 1 shared Baptiste LegrandiD· 1 shared Chames KermiiD· 1 shared Domenico MaioranoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Jean‐Marc PascussiORCID

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2 papers

Recent·Most cited

Cancer BiologyCell ReportsPeer-reviewedJul 1, 2026

A non-catalytic function for Rad18 in sustaining glioblastoma proliferation

Nour El Houda Benbahouche, Antoine Aze, Aurore Siegfried…·Domenico Maiorano

This study identifies a non-catalytic role for Rad18 in sustaining glioblastoma proliferation and proposes it as a therapeutic target.

DOI 10.1016/j.celrep.2026.117638

humanexperimental assay

𝕏 PostBluesky

Cancer BiologyOncogenesisPeer-reviewedAug 30, 2025

Targeting Pregnane X Receptor with a Potent Agonist-Based PROTAC to Delay Colon Cancer Relapse

Lucile Bansard, Guillaume Laconde, Vanessa Delfosse…·Jean‐Marc Pascussi

This study designs and tests a PXR agonist-based PROTAC (JMV7048) that degrades PXR in cancer cells, reducing chemoresistance and delaying colon cancer relapse.

8 citations

humanexperimental assay

𝕏 PostBluesky