Author

Jean‐Marc Pascussi

Centre National de la Recherche ScientifiqueORCID 0000-0002-5168-5383Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

Julie PannequiniD· 3 shared Alain ChavanieuiD· 2 shared Lucile Bansard· 2 shared Alexandre DavidiD· 1 shared Amandine BastideiD· 1 shared Anne‐Alicia GonzaleziD· 1 shared Anthony R. MartiniD· 1 shared Antoine Aze· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersCancer Biology

Julie PannequinORCID

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3 papers

Recent·Most cited

Cancer BiologyCell ReportsPeer-reviewedJul 1, 2026

A non-catalytic function for Rad18 in sustaining glioblastoma proliferation

Nour El Houda Benbahouche, Antoine Aze, Aurore Siegfried…·Domenico Maiorano

This study identifies a non-catalytic role for Rad18 in sustaining glioblastoma proliferation and proposes it as a therapeutic target.

DOI 10.1016/j.celrep.2026.117638

humanexperimental assay

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJan 9, 2026

A Novel miR-4745-KLC2 Axis Regulates Cancer Stem Cell Traits in Colorectal Cancer

Kuldeep Lahry, Pauline Barraja, Julie Ripoll…·Chris Planque

This study identifies miR-4745 as a regulator of cancer stem cell traits in colorectal cancer, showing it inhibits CSC self-renewal and chemoresistance by targeting KLC2.

DOI 10.64898/2026.01.07.697660

humanbulk RNA-seq

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Cancer BiologyOncogenesisPeer-reviewedAug 30, 2025

Targeting Pregnane X Receptor with a Potent Agonist-Based PROTAC to Delay Colon Cancer Relapse

Lucile Bansard, Guillaume Laconde, Vanessa Delfosse…·Jean‐Marc Pascussi

This study designs and tests a PXR agonist-based PROTAC (JMV7048) that degrades PXR in cancer cells, reducing chemoresistance and delaying colon cancer relapse.

8 citations

humanexperimental assay

𝕏 PostBluesky