Author
Centre National de la Recherche ScientifiqueORCID 0000-0002-9956-373XUnclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Dana Naim, Zouheir HOUHOU, Florent Cauchois…·Serge Roche
This study identifies SLAP as a tumor suppressor that limits SFK activity in colonic epithelial cells, preventing tumorigenesis and hyperproliferation.
Nour El Houda Benbahouche, Antoine Aze, Aurore Siegfried…·Domenico Maiorano
This study identifies a non-catalytic role for Rad18 in sustaining glioblastoma proliferation and proposes it as a therapeutic target.
Valentin Gensbittel, Zeynep Yesilata, Louis Bochler…·Jacky G. Goetz
This study shows that tumor cell viscosity affects their ability to circulate and extravasate, influencing metastasis.
Kuldeep Lahry, Pauline Barraja, Julie Ripoll…·Chris Planque
This study identifies miR-4745 as a regulator of cancer stem cell traits in colorectal cancer, showing it inhibits CSC self-renewal and chemoresistance by targeting KLC2.
Lucile Bansard, Guillaume Laconde, Vanessa Delfosse…·Jean‐Marc Pascussi
This study designs and tests a PXR agonist-based PROTAC (JMV7048) that degrades PXR in cancer cells, reducing chemoresistance and delaying colon cancer relapse.
Mounira Chalabi‐Dchar, Olivia Villeronce, Julie Ripoll…·Jean‐Jacques Diaz
The paper shows 5-FU induces translational reprogramming in colorectal cancer cells, enhancing drug tolerance through pro-tumoral gene expression and IL-8 overexpression.