Author

Yvette Lopez-Diaz

University of Massachusetts Chan Medical SchoolORCID 0009-0009-8609-344XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Arthur M. MercurioiD· 1 shared Hadiya K. GiwaiD· 1 shared Jason Robert PitarresiiD· 1 shared Jessica PeuraiD· 1 shared Junhui LiiD· 1 shared Karl J. SiminiD· 1 shared Katherine C. MurphyiD· 1 shared Kelly D. DeMarcoiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Arthur M. MercurioORCID

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1 paper

Recent·Most cited

Cancer BiologyCancer ResearchPeer-reviewedSep 3, 2025

MYC and p53 alterations cooperate through VEGF signaling to repress cytotoxic T cell and immunotherapy responses in prostate cancer

Katherine C. Murphy, Kelly D. DeMarco, Lin Zhou…·Marcus A. Ruscetti

This study shows that MYC and p53 alterations in prostate cancer cooperate via VEGF signaling to suppress T cell activity and immunotherapy responses, and that targeting VEGFR2 can enhance immunotherapy efficacy.

10 citationstop 5%

mousehuman

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