Adrβ2 in skeletal muscle cells is required for exercise-induced Pgc1α but not for metabolic benefits of exercise on diet-induced obesity
Marco Galvan, Mina Fujitani, Jasmine Dushime…·Teppei Fujikawa
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The University of Texas Southwestern Medical CenterORCID 0009-0009-9099-1218Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Marco Galvan, Mina Fujitani, Jasmine Dushime…·Teppei Fujikawa
Aileen H. Lee, Lucie Orliaguet, Yun‐Hee Youm…·Vishwa Deep Dixit
This study shows that cysteine depletion induces adipose browning and weight loss in mice, mediated by noradrenaline signaling via β3-adrenergic receptors, without requiring UCP1.
Marco Galvan, Mina Fujitani, Samuel R. Heaselgrave…·Teppei Fujikawa
The paper develops and characterizes Sf-1-Flp mice to study VMH-regulated physiology, showing their utility in optogenetic experiments and demonstrating the role of Adrβ2 in skeletal muscle PGC-1 response.