Author

Andrea Enriquez

Indiana University BloomingtonORCID 0009-0009-9236-6707Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Hui‐Chen LuiD· 3 shared Sen YangiD· 3 shared Jason M. TennesseniD· 2 shared Jui-Yen HuangiD· 2 shared Karen LingiD· 2 shared Paymaan Jafar‐NejadiD· 2 shared Zhen‐Xian NiouiD· 2 shared Anoosha Sri· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersNeuroscience

Hui‐Chen LuORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintApr 21, 2026

NMNAT2-SARM1 Axis Drives Redox Failure and Disrupts APP Processing in Neurons

Andrea Enriquez, Sen Yang, Karen Ling…·Hui‐Chen Lu

This study shows that NMNAT2 loss disrupts APP processing in neurons by causing redox failure and proteostasis disruption, with SARM1 playing a key role in this process.

DOI 10.64898/2026.04.16.718990

mouseproteomics

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NeurosciencebioRxivPreprintMay 5, 2025

NAD+ reduction in glutamatergic neurons triggers fatty acid catabolism and neuroinflammation in the brain, mitigated by SARM1 deletion

Zhen‐Xian Niou, Sen Yang, Andrea Enriquez…·Hui‐Chen Lu

The paper shows that loss of NMNAT2 in glutamatergic neurons causes metabolic shifts and neurodegeneration, which are mitigated by SARM1 deletion.

1 citation

mouseproteomics

𝕏 PostBluesky

NeurosciencebioRxivPreprintFeb 6, 2022

NAD homeostasis maintained by NMNAT2 supports vesicular glycolysis and fuels fast axonal transport in distal axons of cortical glutamatergic neurons in mice

Sen Yang, Zhen‐Xian Niou, Andrea Enriquez…·Hui‐Chen Lu

This study shows NMNAT2 maintains NAD redox potential in axons to support glycolysis and fast transport, preventing axonal degeneration in mice.

1 citation

mouseexperimental assay

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