Xingwu Ge

The paper maps thylakoid membrane biogenesis in Chlamydomonas reinhardtii using integrated imaging and proteomics, revealing decentralized synthesis and hierarchical assembly of photosynthetic complexes.

This study identifies the structured hairpin region of IM30 as the driver of stress-induced condensate formation in cyanobacteria, linking membrane stress, pH changes, and phase separation.

The paper shows IM30 binds membranes via a conserved helical hairpin, initiating assembly into higher-order structures that mediate membrane remodeling, revealing a conserved mechanism across ESCRT-III superfamily members.

Cryo-ET of 169 nm β-carboxysomes from low-light Synechococcus elongatus reveals ~639 Rubiscos in concentric layers with CcmM bound at RbcL grooves; QconCAT proteomics yields the complete absolute protein stoichiometry.

This study investigates the role of CsoS2-M in carboxysome shell assembly and shaping, revealing its function in enhancing shell protein association and recruiting CsoS2A for Rubisco packaging.