Author

Han Wan

Yale UniversityORCID 0009-0009-9678-4500Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:long-read sequencing· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Anna Marie PyleiD· 3 shared Rafael de Cesaris Araujo TavaresiD· 2 shared Adam WilliamsiD· 1 shared Akiko IwasakiiD· 1 shared Ananthanarayanan KumariD· 1 shared Bao WangiD· 1 shared Craig B Wilen· 1 shared Craig B. WileniD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersMolecular Biology

Anna Marie PyleORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintAug 7, 2023

Discovery of a Well-Folded Protein Interaction Hub Within the Human Long Non-Coding RNA NORAD

Ananthanarayanan Kumar, Han Wan, Zion R. Perry…·Anna Marie Pyle

The paper identifies a structured protein interaction hub in the long non-coding RNA NORAD using biochemical and sequencing methods.

DOI 10.1101/2023.08.07.552337

humanproteomics

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BiochemistryMolecular CellPeer-reviewedFeb 1, 2021

Comprehensive in-vivo secondary structure of SARS-CoV-2 genome reveals novel regulatory motifs and mechanisms

Nicholas C Huston, Han Wan, Rafael de Cesaris Araujo Tavares…·Anna Marie Pyle

This study determines the complete secondary structure of the SARS-CoV-2 genome in infected cells, revealing novel regulatory motifs and conserved structural features across beta coronaviruses.

DOI 10.1016/j.molcel.2020.12.041

viruslong-read sequencing

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BioinformaticsbioRxivPreprintMay 6, 2020

Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium

Neal G. Ravindra, Mia Madel Alfajaro, Victor Gasque…·Craig B. Wilen

Time-course single-cell RNA sequencing of infected human bronchial epithelial cultures reports ciliated cells as a major target, with tropism later widening to basal and club cells.

74 citations

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