Author

Jesse Buffington

National Cancer InstituteORCID 0009-0009-9751-7199Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Assay:clinical cohort / trial· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Andrew S. LeeiD· 1 shared Blerta XhemalçeiD· 1 shared Brittney VoigtiD· 1 shared Hung‐Che KuoiD· 1 shared Ilya J. FinkelsteiniD· 1 shared Jittiporn ChaisaingmongkoliD· 1 shared Kamyab JavanmardiiD· 1 shared Kuang HuiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Andrew S. LeeORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintApr 10, 2026

Enteroviral epitope mimicry enables NK cell-mediated targeting of ASPH in hepatocellular carcinoma

Man‐Hsin Hung, Qin Li, L. Wang…·Xin Wei Wang

The paper identifies anti-CE1 antibodies that reduce HCC incidence and mortality by mediating NK cell ADCC against ASPH-expressing tumor cells through epitope mimicry.

1 citation

humanproteomics

𝕏 PostBluesky

Molecular BiologyNature BiotechnologyPeer-reviewedOct 23, 2025

Discovery and Engineering of Retrons for Precise GenomeEditing

Jesse Buffington, Hung‐Che Kuo, Kuang Hu…·Ilya J. Finkelstein

This paper discovers and engineers retron-based gene editors for precise genome editing in mammalian cells and vertebrates, achieving high efficiency with novel reverse transcriptases and delivery strategies.

13 citations

humanmouse

𝕏 PostBluesky