Author

Adam J. Brownstein

University of California, Los AngelesORCID 0009-0009-9900-2690Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Candance Guerrero· 1 shared Christopher J. RhodesiD· 1 shared Emilia M. Swietlik· 1 shared Jason S. HongiD· 1 shared Jeffrey C. BlakeiD· 1 shared Jenna B. MendelsoniD· 1 shared Joanna Pepke‐ŻabaiD· 1 shared Kevin J. MurrayiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Candance Guerrero

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1 paper

Recent·Most cited

Molecular BiologyJACC Basic to Translational SciencePeer-reviewedMay 30, 2026

Impaired Lung BCAA Metabolism Promotes Ferroptosis and Resultant Pulmonary Arterial Hypertension-Associated Hepatopathy

Madelyn J. Blake, Jason S. Hong, Adam J. Brownstein…·Kurt W. Prins

This study shows that impaired BCAA metabolism promotes ferroptosis, leading to pulmonary arterial hypertension and associated liver disease, and that targeting BCAA metabolism can alleviate these effects.

1 citation

humanmouse

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