Fucosylated and non-fucosylated alpha2,3 sialosides were detected on the bovine mammary gland tissues

Takahiro Hiono; Tatsuru Morita; Keigo Kosenda; Yuki Otani; Osamu Ichii; Norikazu Isoda; Yoshihiro Sakoda

doi:10.1101/2024.07.29.605565

MicrobiologybioRxivJul 29, 2024

Preprint

Fucosylated and non-fucosylated alpha2,3 sialosides were detected on the bovine mammary gland tissues

Takahiro Hiono iD, Tatsuru Morita iD, Keigo Kosenda iD, Yuki Otani, Osamu Ichii iD, Norikazu Isoda iD, Yoshihiro Sakoda iD

Abstract

Receptors for high pathogenicity avian influenza viruses (HPAIVs) in the mammary glands of dairy cattle were detected using various recombinant hemagglutinins (rHAs). Results demonstrated the presence of fucosylated and non-fucosylated 2,3 sialosides, which were typically targeted by the HA of clade 2.3.4.4b HPAIVs.

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