Stephanie N. Langel

Intranasal adenovirus type 5 influenza vaccination enhances milk antibody responses and passive transfer to neonatal ferrets

This study evaluates intranasal adenovirus type 5 influenza vaccination in pregnant and lactating ferrets, finding it enhances milk antibody responses and passive transfer to neonatal offspring.

Route of Adenovirus Type 5-Vectored Influenza Vaccination Shapes Systemic and Mucosal Immunity in a Maternal-Neonatal Pig Model

This study evaluates the effectiveness of different vaccination routes for a huAd5-vectored influenza vaccine in pregnant pigs, showing that intranasal and intramuscular routes induce stronger maternal immunity and passive transfer to piglets than oral.

Pregnant Dairy Heifers Express Influenza A Virus Receptors in the Mammary Gland

The paper identifies 2,3-linked sialic acids in the mammary glands of pregnant dairy heifers, suggesting susceptibility to H5N1 influenza virus infection.

Susceptibility of bovine respiratory and mammary epithelial cells to avian and mammalian derived clade 2.3.4.4b H5N1 highly pathogenic avian influenza viruses

This study compares the replication ability of avian and mammalian-derived clade 2.3.4.4b H5N1 viruses in epithelial cells from different species, finding that mammalian strains replicate more broadly.

Intramammary infection of bovine H5N1 influenza virus in ferrets leads to transmission in suckling neonates

This study shows that H5N1 influenza virus in milk from infected lactating ferrets can transmit to suckling neonates, causing mortality.

Metabolic immaturity of newborns and breast milk bile acids are the central determinants of heightened neonatal vulnerability to norovirus diarrhea

This study identifies metabolic immaturity in newborns and maternal bile acids in breast milk as key factors increasing vulnerability to norovirus diarrhea.