DeepSleep: Fast and Accurate Delineation of Sleep Arousals at Millisecond Resolution by Deep Learning

Sleep arousals are transient periods of wakefulness punctuated into sleep. Excessive sleep arousals are associated with many negative effects including daytime sleepiness and sleep disorders. High-quality annotation of polysomnographic recordings is crucial for the diagnosis of sleep arousal disorders. Currently, sleep arousals are mainly annotated by human experts through looking at millions of data points manually, which requires considerable time and effort. Here we present a deep learning approach, DeepSleep, which ranked first in the 2018 PhysioNet Challenge for automatically segmenting sleep arousal regions based on polysomnographic recordings. DeepSleep features accurate (area under receiver operating characteristic curve of 0.93), high-resolution (5-millisecond resolution), and fast (10 seconds per sleep record) delineation of sleep arousals.