Genetic diversity of the enteroviruses detected from Cerebrospinal fluid (CSF) samples of patients with suspected aseptic meningitis in northern West Bank, Palestine in 2017

Abstract

Background Background Materials and Methods Results Discussion Reference Human enterovirus (HEV) is a non-enveloped RNA genus of the family Picornaviridae with more than 107 genotypes. HEV is divided into 4 HEV species designated HEVA to D, based on the sequences analysis of the partial or complete VP1 region of the viral genome[1]. The VP1 are immunodominant capsid proteins that contain the neutralization antigenic determinants which correlate well with serotyping and are used for HEV genotyping[2].\n\nHEVs are associated with several diverse clinical manifestations including mild febrile illness, gastroenteritis, respiratory tract infection, neonatal sepsis-like illness and aseptic meningitis as the most frequent infections caused by HEV that occurs as sporadic and/or outbreaks of varying ...