Y. F. Chan

Transposable element insertions are associated with Batesian mimicry in the pantropical butterfly Hypolimnas misippus

This study identifies transposable element insertions at the M locus in Hypolimnas misippus that drive adaptive atavism for Batesian mimicry of Danaus chrysippus.

Repeated genetic adaptation to high altitude in two tropical butterflies

This study identifies genetic regions under selection in two tropical butterflies adapted to high altitude, showing that standing variation and introgression from high-altitude specialists contribute to parallel adaptation.

Genetic studies of human-chimpanzee divergence using stem cell fusions

This paper develops a stem cell fusion approach to map human-chimpanzee genetic differences by analyzing gene expression in tetraploid iPSCs and identifying cis- and trans-acting regulatory elements.

Genomics of altitude-associated wing shape in two tropical butterflies

This study investigates the genomic basis of altitude-associated wing shape differences in two Heliconius butterfly species, finding a polygenic basis and identifying candidate genes involved in wing morphogenesis.

SARS-CoV-2 lineage B.6 is the major contributor to transmission in Malaysia

This study analyzes SARS-CoV-2 genome sequences from Malaysia to show that lineage B.6 became the dominant cause of community transmission following a religious mass gathering, with global implications.

Haplotype tagging reveals parallel formation of hybrid races in two butterfly species

Haplotagging reveals parallel formation of a novel hybrid race in two Heliconius butterfly species through divergent haplotypes at major wing pattern loci.

A major locus controls a biologically active pheromone component in Heliconius melpomene

This study identifies a major genetic locus controlling octadecanal production in Heliconius melpomene, a biologically active pheromone component involved in mate choice.

Independent evolution towards large body size in the distinctive Faroe Island mice

The paper identifies 102 genetic loci associated with body size in Faroe Island mice, finding they evolved independently from other populations.

Electrostatic interactions at the five-fold axis alter heparin-binding phenotype and drive EV-A71 virulence in mice

This study shows that electrostatic interactions at the five-fold axis of EV-A71 influence heparin-binding and drive virulence in mice by altering viremia and neuroinvasion.

An integrative genomic analysis of the Longshanks selection experiment for longer limbs in mice

This study analyzes the genomic changes in mice selectively bred for longer limbs, identifying polygenic adaptation and major-effect loci linked to bone growth regulation.