msVolcano: a flexible web application for visualizing quantitative proteomics data.

Abstract

We introduce msVolcano, a web application, for the visualization of label-free mass spectrometric data. It is optimized for the output of the MaxQuant data analysis pipeline of interactomics experiments and generates volcano plots with lists of interacting proteins. The user can optimize the cutoff values to find meaningful significant interactors for the tagged protein of interest. Optionally, stoichiometries of interacting proteins can be calculated. Several customization options are provided to the user for flexibility and publication-quality outputs can also be downloaded (tabular and graphical).\n\nAvailability: msVolcano is implemented in R Statistical language using Shiny and is hosted at server in-house. It can be accessed freely from anywhere at http://projects.biotec.tudresden.de/msVolcano/