Marek Gierliński

This study shows that disrupting quorum-sensing pathways in Bacillus subtilis provides a competitive advantage by increasing growth rate, with such mutations found in ~16% of isolates.

This paper identifies a new family of T6SS pore-forming effectors in Serratia marcescens, showing distinct ion selectivity and broader target range compared to existing toxins.

This study identifies NSUN1-mediated m5C RNA methylation as a driver of TDP-43 cytoplasmic accumulation and neurotoxicity in ALS/FTD.

The paper identifies SRPK-mediated phosphorylation of MAP1S, showing it regulates proteolytic processing and microtubule binding during neurodevelopment.

This study shows that a NOTCH1 mutation affects NICD stability and disrupts segmentation clock function in hiPSC-derived PSM cells and somitoids.

This study shows that excluding condensin I from the nucleus during prophase allows condensin II to complete sister chromatid resolution, ensuring correct chromosome segregation.

This study identifies an ISR-independent role of GCN2 in preventing excessive ribosome biogenesis and mRNA translation, with implications for cancer therapy.

This study evaluates DGE tools' performance in Arabidopsis thaliana, finding that their false positive rates are not strongly affected by transcriptome complexity.

Proteus is an open-source R package with Shiny interactive visualization that aggregates MaxQuant proteomics evidence data and uses limma to improve differential expression sensitivity over Perseus random imputation.

The paper develops a protocol to generate human neuromesodermal and spinal cord progenitors in vitro, validates it with RNA-Seq, and identifies new pathways in neural differentiation.